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Stock Name:

PROYA

Stock Code:603605

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FAQs

Substances that pose a safety risk are substances brought in from raw materials, or generated or brought in during the production process of daily-use chemical products, which may cause potential harm to human health.

  • What are the common hazards of substances that pose a safety risk?

    ? Acute toxicity: refers to the health hazards of substances that pose a safety risk in a short period of exposure, including acute oral toxicity and acute percutaneous toxicity. Generally, substances that pose a safety risk with moderate acute toxicity or above can easily cause health hazards
     
    ? Irritation/corrosion: refers to the irritation or corrosion caused by substances that pose a safety risk to the skin or eyes
     
    ? Skin sensitization: refers to skin allergies caused by repeated exposure to substances that pose a safety risk
     
    ? Skin phototoxicity: refers to such skin symptoms as redness and swelling, fever, itching and herpes under ultraviolet radiation after one exposure to certain substances that pose a safety risk
     
    ? Skin photomorphic reaction: refers to abnormal skin symptoms caused by repeated exposure to substances that pose a safety risk under ultraviolet radiation
     
    ? Genotoxicity: refers to the possibility of genotoxicity caused by substances that pose a safety risk, including genetic mutations and chromosomal aberrations
     
    ? Repeated dose toxicity: refers to the health hazard effects caused by repeated exposure to substances that pose a safety risk within a certain period of time, resulting in target organ lesions. It can be caused by oral, percutaneous and inhalation routes
     
    ? Reproductive and developmental toxicity: refers to the impairment of reproductive function, early embryonic development (e.g., teratogenic), pre- and postnatal development, maternal function, and embryonic and fetal development caused by exposure to cosmetic substances that pose a safety risk
     
    ? Chronic toxicity/carcinogenicity: refers to toxic reactions or carcinogenesis caused by long-term exposure to substances that pose a safety risk in certain ways
  • How can we control the potential substances that pose a safety risk in the product?

    Health risks caused by substances that pose a safety risk can lead to adverse reactions in the human body. For example, adverse reactions caused by the use of cosmetics are divided into general adverse reactions and serious adverse reactions.
     
    General adverse reactions have a variety of manifestations, the most common of which are itching, burning and tightness of the skin, erythema, papules, edema, etc. In severe cases, blisters, vesicles, exudation, etc., and even systemic damage; some cosmetics can also lead to abnormal skin pigmentation, hair damage, mouth and lip rashes, finger/toenail deformities, and cause or aggravate acne. From a diagnostic point of view, they include: cosmetic contact dermatitis, cosmetic acne, cosmetic hair damage, cosmetic nail damage, cosmetic photosensitive dermatitis, cosmetic skin pigmentation abnormalities, cosmetic contact urticaria, cosmetic labyrinthitis, etc.
     
    Serious adverse reactions refer to severe damage to the skin (including mucous membranes) and its appendages caused by cosmetics in a large or deeper area, as well as systemic damage to other organs and tissues. They usually fall into the following five categories:
     
    ? resulting in temporary or permanent loss of function, affecting normal human and social functions, such as obvious cosmetic changes, lasting lesions that do not heal, scar formation, permanent hair loss, etc.
    ? leading to systemic damage, such as sepsis, abnormal liver and kidney function, anaphylaxis, etc.
    ? resulting in congenital abnormalities or teratogenicity
    ? leading to death or a life-threatening situation
    ? other serious categories that require hospitalization as deemed necessary by medical institutions
  • How can we control the potential substances that pose a safety risk in the product?

    Substances that pose a safety risk in products are usually brought into the product as impurities in raw materials or packaging materials. Some impurities are micro components that exist naturally in raw materials and are technically unavoidable; some impurities are generated during the production process, as existing raw material purification technology cannot reach a 100% success rate; and some impurities are brought into the product by packaging materials.
     
    Effective quality control methods are needed to prevent the substances that pose a safety risk brought into the product from causing human health hazards, which generally include the following:
     
    ? Quality control of raw materials and packaging materials: review the quality control standards provided by the raw material suppliers and conduct the necessary testing on raw materials and packaging materials for risky substances
     
    ? Production process control: follow the relevant provisions of good manufacturing practices to produce goods, and minimize the introduction of substances that pose a safety risk during the production process
     
    ? Safety assessment and testing of finished products: perform effective safety risk assessments on finished products, evaluate the extent of their hazards to human health, and ensure that the products do not cause human health risks; at the same time, carry out risky substance testing, stability testing, corrosion challenge testing, toxicology testing, and human safety testing on the products
Product ingredient disclosure
The time of product ingredient disclosure lags behind the requirement. If an inconsistency exists, please refer to the registration information at the National Medical Products Administration. Here's the links to see the detailed product registration information:
China Specialty Cosmetics Registration Information
China General Cosmetics Recordation Information
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